Effect of Natto on Intestinal Diseases of Mice

  • Jing Zhang


In order to study the relationship between lactic acid bacteria extracted from natto and intestinal diseases in mice, and the regulation effect of intestinal flora in mice with intestinal diseases, in this research, the isolation and screening of lactic acid bacteria from fermented natto were introduced at first, and then the establishment of a mouse model of intestinal disease caused by the imbalance of intestinal flora induced by antibiotics, as well as the collection of mouse feces and the detection of various indexes of the intestinal tract were introduced. Finally, the regulating effect of lactic acid bacteria and oligosaccharides extracted from natto on the microflora of mouse intestinal flora was analyzed. The results showed that the lactic acid bacteria and oligosaccharides showed very good inhibition of intestinal immune dysfunction caused by lincomycin hydrochloride. The mixed lactic acid bacteria and oligosaccharides could be used for preventing intestinal disorders. It was also found that when the mixed lactic acid bacteria and fermented milk were increased, it had a good inhibitory effect on the growth of bacteria, and can improve the environment of the intestinal flora. It can also improve the intestinal diseases. The research in this paper has certain reference and guiding significance for the treatment of intestinal diseases.