Exercise Training on Glucose Lipid Metabolism in Rats with Metabolic Syndrome

  • Jichao Niu

Abstract

Metabolic syndrome is a multiple risk factor of cardiovascular, such as individual aggregation of obesity, disorder of blood lipid, abnormal glucose tolerance, and elevated blood pressure and so on. With the development of economy and the change of life style, the incidence of metabolic syndrome increases with age. This article observes the effects of exercise training on glucose and lipid metabolism in rats and serum leptin (LEP), adiponectin (ADPN), free fatty acid (FFA) with metabolic syndrome. Thirty Wistar male rats were divided into exercise group and model group randomly after establishing metabolic syndrome (MS) rat model by high fat, high sugar and high salt method. Fifteen non-model rats were used as control group. The exercise group was given exercise training for 6 weeks. Detect the level of blood lipid, blood sugar, body weight, obesity index, blood pressure (BP), fasting serum insulin (Fins), LEP, ADPN and FFA in each group of rats. The results showed that the body weight, obesity index, blood lipid, blood sugar, blood pressure, Fins, LEP, ADPN and FFA levels in the model group were higher than those in the sham operation group (P < 0.05) significantly, while the ADPN levels were significantly lower (P < 0.05); compared with the sham group, the body weight, obesity index, blood lipid, blood sugar, blood pressure, Fins, LEP, ADPN and FFA levels in the exercise group were lower than those in the model group(P < 0.05) significantly, ADPN level increased significantly (P < 0.05) compared to the model group. Exercise can reduce glucose lipid metabolism in rats with metabolic syndrome, which may be related to its inhibition of LEP and FFA expression and promotion of AD-PN expression.

Published
2019-08-04