Effects of Exercise Training on Free Radical Metabolism of Myocardium, Liver and Quadriceps in Mice

  • Lei Bai

Abstract

To investigate the effects of 6-week continuous and intermittent treadmill exercise training on free radical metabolism in myocardium, liver and quadriceps of mice. In this paper, 24 male Sprague-Dawley rats were randomly divided into a quiet control group (S group), a continuous training group (C group) and a long-term rest training group (I group), a total of 3 groups, 8 in each group. The sports team’s advanced behavioral period of 1 week is an adaptive running platform. The adaptive treadmill training was carried out according to the following three levels of load: 15 m/min x 20 min on day 1-2, 18 m/min x 20 min on day 3-4, and 21 m/min x 20 min on day 5-6. During formal training, the quiet group did not exercise and was kept normally for 6 weeks. The first week of the sports group started the treadmill training at a speed of 22 m/min, and then increased at a rate of 1 m/min every week until the 6th week of 27 m/min, 6 days/week. Among them, the continuous training group trains once a day for 40 minutes; the long-term rest group trains 2 groups every day, each group trains for 20 minutes, and the group rests for 3 hours. After 6 weeks of training, no water is allowed. After fasting for 24 hours, 5 ml of apical blood, heart muscle, liver, quadriceps, soleus muscle, gastrocnemius muscle and other tissues were placed in the refrigerator at -80 °C for testing. The whole process was carried out on ice. Finally, the MDA, SOD, T-AOC and other indicators of rats were determined by colorimetry (kit). The results indicate that exercise can play a role in clearing free and enhancing antioxidant activity in the body.

Published
2019-08-04